Calcium pump activity of red blood cell membrane and the ratio of inner and outer covers of red blood cells after neonatal hypoxic-ischemic encephalopathy.

Abstract

 The calcium content in red blood cells increases before calcium supplementation in neonates with hypoxic-ischemic encephalopathy (HIE), indicating the existence of calcium influx in HIE. This study emphatically proves that after calcium supplementation in HIE and hypocalcemia, the total plasma calcium Increase, but the calcium [Ca2+] concentration in red blood cells does not change significantly, and there is no correlation between the two, indicating that HIE and hypocalcemia can be appropriately supplemented with calcium. It will not cause calcium overload and cause cell damage.