Newborns stop battle with coronary heart disease
Keywords:
neonates; lipid abnormalities; coronary heart disease; screeningAbstract
In this article, 33 full-term healthy newborns with family history of coronary heart disease (observation group) and 174 healthy full-term newborns without family history of coronary heart disease (control group) had serum cholesterol (TC), triglyceride (TG), apolipoprotein AI ( Comparing the levels of measured values of ApoAI), apolipoprotein B (ApoB), and lipoprotein (a) [LP(a)], it was found that the mean value of ApoB in the observation group was significantly higher than that in the control group (P=0.0015), with a highly significant difference ; The mean value of LP(a) and the frequency of increased concentration in the observation group were significantly higher than those in the control group (P<0.05, 0.01 respectively), with significant differences. It shows that ApoB and LP(a) have obvious genetic tendencies and are reliable indicators for screening newborns for lipid abnormalities. It also shows that newborns with a family history of coronary heart disease have a significantly increased risk of developing coronary heart disease. Neonatal lipids Screening for qualitative abnormalities is one of the important means to reduce the incidence of coronary heart disease.