Prognosis and influencing factors of perinatal hypoxic brain injury

Abstract

 The prognosis and influencing factors of 39 neonates with a clear history of perinatal hypoxia (12 cases of severe asphyxia and 27 cases of HIE) were analyzed. The intellectual development level of 35 surviving children was measured by the Gesell method at 3, 6, 9, and 12 months of age. Good prognosis and basically normal accounted for 82.05%, and poor prognosis accounted for 17.95%. Multiple stepwise regression analysis showed that gestational age, birth weight, cerebral edema, and intracranial hemorrhage severity were closely related to prognosis. Further single factor analysis found that gestational age <34 weeks, birth weight <1500g, cerebral edema lasting for more than 4 days, and cranial hemorrhage Internal bleeding of III to IV degrees poses the greatest threat to prognosis and can be used as a reference for early evaluation of prognosis. Early intervention in children with brain injury can help tap into developmental potential and improve prognosis on the original basis.
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